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 Graduate Training in Computation and Informatics in Biology and Medicine at the University of Wisconsin-Madison
Computation and Informatics in Biology and Medicine
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Burr H. Settles

Computer Sciences Doctoral Training Program

Dept. of Computer Sciences

Faculty Supervisor: Mark Craven

Email: bsettles@cs.wisc.edu

Computer Sciences web page: http://www.biostat.wisc.edu/~bsettles/

265-3712

As DNA sequencing projects complete more genomes, the emphasis is shifting from sequencing the genetic code to actually understanding the functions of and relationships between genes and related molecules. This has lead to a recent boom in biomedical research, improving both the quality and quantity of biomolecular knowledge with each new publication (much of this literature being in electronic format). While this is certainly beneficial to researchers, it also creates a load of information too overwhelming for a research group - let alone an individual - to read entirely. To help promote successful research directions, biomedical scientists could benefit from tools for automated Natural Language Processing (NLP) – a branch of Artificial Intelligence research seeking ways to perform effective computerized tasks using natural language. Specifically, we would like to have intelligent machines that can automatically cull the wealth of electronic literature, annotate documents, and build structured knowledge-bases about interactions between proteins, genes, RNA, cell loci, etc. This information can populate more structured reference databases, be analyzed with data mining techniques to discover new relationships, and even launch new research directions. The first step in such a system, however, is identifying the terms of interest (e.g., genes, mRNA molecules, and proteins) in these texts. This is the focus of our research.

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http://www.cs.wisc.edu/~bsettles/vita.html

Publications

Search for publications by Burr Settles (Pub Med, Cite Seer)

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