Predoctoral Trainee

Brian Teague Cellular & Molecular Biology Graduate Program Faculty Supervisor: David Schwartz Email: teague@wisc.edu 265-5401

The broad aim of my research is to discover and characterize structural polymorphisms in the human genome. Recent work in our laboratory and others has uncovered a heretofore uncharacterized class of human polymorphisms termed “structural” variants, composed of insertions, deletions, inversions and other structural changes ranging in size from sub-kilobase to multi-megabase. Though these polymorphisms have been shown to be phenotypically relevant, technological limitations have hampered their discernment and characterization. I am applying Optical Mapping to this problem. Optical Mapping is a technology that enables the construction of whole-genome restriction maps in an automated, high-throughput manner from single genomic DNA molecules. My focus is on analysis of an enormous data set of many “normal” human cell lines, enabled through novel experimental and computational approaches.

CV

2007 CV (.pdf format)

Publications

Search for publications by Brian Teague (Pub Med)

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File last modified: August 13, 2003
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