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 Graduate Training in Computation and Informatics in Biology and Medicine at the University of Wisconsin-Madison
Computation and Informatics in Biology and Medicine
  Home  >  People  >  Predoctoral Trainees   >  Aaron Darling Program Details

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Predoctoral Trainee

Eric Lantz

Computer Sciences Doctoral Program

Faculty Supervisor: David Page

Email: lantz@cs.wisc.edu

262-6601

Probabilistic graphical networks such as Bayesian networks have been applied to a variety of tasks, including predicting gene interaction networks. Searching the complete space of possible networks is intractable for problems of interesting size, so simplifications must be made. However, these simplifications also restrict the types of relationships that can be learned exclusively from data. One type of relationship we would like to be able to elucidate is “correlation immune” functions, which are characterized by the inability to detect any pairwise correlation between relevant variables. We augment a commonly used Bayesian network structure learning algorithm called sparse candidate with a technique called skewing to randomly permute the data distribution multiple times, causing relevant variables to stand out against irrelevant variables. Good results have been achieved with synthetic data, and we will fit to appropriate biological datasets.

CV

Computer Sciences web page: http://www.cs.wisc.edu/~lantz

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